Aviplus® S

AviPlus®S è la 3a generazione di prodotti Vetagro per suini. Una miscela sinergica di acidi organici e composti natural-identici. AviPlus®S è registrato a livello europeo come additivo.

EFFICIENZA

AviPlus® S è la 3a generazione di prodotti innovativi Vetagro per suini.

AviPlus® S è un additivo zootecnico registrato presso l’Unione Europea che migliora l’accrescimento e l’efficienza alimentare in suini sani.

Condizioni quali stress, enteriti e disbatteriosi, avendo un effetto negativo sulla salute, l’integrità ed il funzionamento intestinale, riducono l’efficienza alimentare. AviPlus® S aiuta a ristabilire l’integrità dell’epitelio intestinale migliorando le performance di crescita e l’indice di conversione alimentare nei suinetti. Il meccanismo d’azione di AviPlus® S si basa sulle proprietà uniche dei suoi ingredienti che in modo sinergico migliorano la funzionalità della barriera intestinale e di conseguenza incrementano l’efficienza dell’assorbimento dei nutrienti e la crescita.

AviPlus® S è tracciabile nelle premiscele, nei mangimi completi e anche nel tratto gastro-intestinale. L'innovazione di AviPlus® S, risultato di oltre 30 anni di esperienza nel mercato globale, è confermata da brevetti internazionali.


APPROVAZIONE EFSA

La Commissione Europea ha approvato l’utilizzo di AviPlus® S come additivo zootecnico con il numero identificativo 4d3 per una sana ed efficace produzione suina. L’effetto di AviPlus® S, come validato ed approvato dall’EFSA (European Food Safety Authority) in condizione europee, permette di incrementare l’accrescimento e l’efficienza alimentare in animali sani.

Trovate il testo completo scaricabile dell’opinione scientifica dell’EFSA nell'elenco sottostante. Per ulteriori informazioni scaricate e leggete la Commission Implementing Regulation (EU) No 1117/2010 del 2 dicembre 2010 dall’elenco sottostante.


Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs

Grilli E., Tugnoli B., Passey J.L., Stahl C.H., Piva A., Moeser A.J.
In: BMC Veterinary Research (2015) 11:96

Organic acids, such as citric and sorbic acid, and pure plant-derived constituents, like monoterpens and aldehydes, have a long history of use in pig feeding as alternatives to antibiotic growth promoters. However, their effects on the intestinal barrier function and inflammation have never been investigated. Therefore, aim of this study was to assess the impact…

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Free versus microencapsulated organic acids in medicated or not medicated diet for piglets.

Piva, A., Grilli, E., Fabbri, L., Pizzamiglio, V., Campani, I.
In: (2006) Proceeding from the 10th International Symposium on Digestive Physiology in Pigs; p. 29. Vejle, Denmark, 25-27 May

Aim of the study was to investigate hte growth performance of weaned piglets fed either a medicated or not medicated diet supplemented with formic64%+lactic36% (FL) acid (11 kg/ton) or a microencapsulated blend of organic acids and flavors (T) (1 kg/ton, Tetracid®S, EU patent 1391155B1, Vetagro srl, Italy). 480 three-weeks old SCAAPAG x Goland piglets were…

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Lipid microencapsulation allows slow release of organic acids and natural identical flavors along the swine intestine.

A. Piva, V. Pizzamiglio, M. Morlacchini, M. Tedeschi and G. Piv
In: Journal of Animal Science (2007) 85:486-493.

The purpose of the present work was to investigate the in vivo concentrations of sorbic acid and vanillin as markers of the fate of organic acids (OA) and natural identical flavors (NIF) from a microencapsulated mixture and from the same mixture non microencapsulated, and the possible consequences on the intestinal microbial fermentation. Fifteen weaned pigs…

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Free versus microencapsulated organic acids in medicated or not medicated diet for piglets

A. Piva, E. Grilli, L. Fabbri, V. Pizzamiglio, I. Campani
In: Livestock Science (2007) 108:214-217

Aim of the study was to investigate the growth performance of weaned piglets fed either a medicated or not medicated diet supplemented with either a blend of formic and lactic (64/36) acids (FL, 11 kg/ton) or a microencapsulated blend of organic acids and flavors (T) (1 kg/ton, Tetracid®S, EU patent 1391155B1,Vetagro srl, Italy). 480 three-week…

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Citric acid and thymol influence gastrointestinal microflora in pigs at weaning.

A. Piva, E. Grilli, M. R. Messina, S. Albonetti, V. Pizzamiglio, I. Cipollini, P. P. Gatta, and G. Zaghini
In: (2007) Proceeding of ADSA-ASAS Joint Annual Meeting, July, 8-21, San Antonio, TX.

Aim of this study was to investigate the role of citric acid (CA) and thymol on growth performance and gastrointestinal microflora in weaning pigs. Ninety-six Landrace × Duroc piglets weaned at 22 days of age (6.7 ± 0.8 kg BW) were divided into four groups of 4 replicates of 6 animals each and assigned to…

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Effects of a microencapsulated blend of organic acids and natural identical flavors supplement to weaned pig diet.

E. Grilli, V. Pizzamiglio, M.R. Messina, L. Jørgensen, H. Maribo, R. Manini, A. Piva
In: (2008) Proceeding of ADSA-ASAS Joint Annual Meeting. July, 7-11, Indianapolis, IN.

Aim of the study was to investigate the effect of a microencapsulated supplement containing citric, sorbic acids, and natural identical flavors on piglets growth performance, mortality, and productivity during the 9 post–weaning weeks. The study was conducted at Danish Pig Production with the approval of the Danish Plant Directorate. Piglets were weaned at 5 weeks…

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Feeding a microencapsulated blend of organic acids and natural identical compounds to weaning pigs improved growth performance and intestinal balance.

E. Grilli, MR. Messina, M. Tedeschi, A. Piva.
In: (2009) Proceedings of XI International Digestive Physiology in Pigs. May, 20-22, Montbrio del Camp, Spain

One-hundred and seventy weaning piglets were divided in two groups, and housed in 34 pens (17 replicates, 5 pigs each). Piglets received a basal diet with or without (control diet, CTR) the addition of a microencapsulated blend of organic acids and natural identical compounds (AviPlus®, EP1391155B1, Vetagro SpA, Italy) at 3 kg/ton. Piglets were weighed…

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Feeding a microencapsualted blend of organic acids and natural identical compounds to weaning pigs improved growth performance and intestinal balance.

E. Grilli, M.R. Messina, M. Tedeschi, A. Piva.
In: (2009) XI Interantional Symposium of Digestive Physiology of Pigs. 20th-22nd May, Montbrió del Camp, Costa Daurada, Spain.

One-hundred and seventy weaning piglets were divided in two groups, and housed in 34 pens (17 replicates, 5 pigs each). Piglets received a basal diet with or without (control diet, CTR) the addition of a microencapsulated blend of organic acids and natural identical compounds (AviPlus®, EP1391155B1, Vetagro Spa, Italy) at 3 kg/ton. Piglets were weighted…

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Aviplus treatment improves growth efficiency in broilers and swine but does not affect intestinal populations of experimentally inoculated with Salmonella

T. R. Callaway, E. Grilli, T. S. Edrington, N. Krueger, R. Anderson, D. W. Pitta, W. E. Pinchak, and A. Piva.
In: (2010) Proceeding of ADSA-CSAS-ASAS Joint Annual Meeting. July, 11-15, Denver, CO.

Organic acids improve growth efficiency in food animals, and can impact the microbial ecology of the gastrointestinal tract. Thus it has been suggested that they could be used to reduce foodborne pathogenic bacterial populations before animals enter the food chain. This study was undertaken to determine the effect of a commercial microencapsulated organic acid product…

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Organic Acids and Their Role in Reduce Foodborne Pathogens in Food Animals

E. Grilli, A. Piva
In: In: On-Farm Strategies to Control Foodborne Pathogens. Callaway, T. R., and T. S. Edrington (Ed.s). NOVA Science Publishers, New York. Pp 183-210

Organic acids (OA) are used since long as food preservative agents, and, in more recent times, as feed additives. The compelling need to use OA in feed date back to the last two decades since the extensive use of antibiotics in farming, both growth promoters (AGP) and therapeuticals, caused concerns on the incidence of antibiotic-resistant…

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Effect of a microencapsulated combination of organic acids and nature‐identical flavors on the growth performance of piglets

R. Barea, F. Rudeaux, A. Piva
In: (2014) 46emes Journées de la Recherche Porcine. 4-5 Février, Paris

The efficiency of a microencapsulated combination of citric acid, sorbic acid, thymol and vanillin (AVIP) on the growth performance of post‐weaning piglets was investigated in the following two sets of studies. A trial was conducted at the VRP Research Center (Denmark) on 768 piglets (110 blocks with approximately 7 piglets each), divided into 3 treatments:…

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Comparaison des performances zootechniques chez le porcelet en post-sevrage avec l’utilisation d’un additif micro-encapsulé dans l’alimentation 1er et 2e âge.

R. Barea, F. Rudeaux, C. Meymerit, A. Piva
In: (2015) 47emes JOURNÉES de la RECHERCHE PORCINE, 3 et 4 Février, Paris.

Les acides organiques (AO) et des arômes identiques naturels (équivalents chimiques des extraits de plantes ; AIN) peuvent affecter positivement la flore microbienne intestinale (Partanen et Mroz, 1999 ; Peñalver et al., 2005), mais aussi induire des effets anti-inflammatoires et bénéfiques sur l'intégrité de la muqueuse intestinale (Grilli et al., 2012). Un des mécanismes d'action…

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Microencapsulated feed additives to reduce Salmonella shedding

E. Grilli, R. Bari, A. Piva, B. Tugnoli, and T. R. Callaway
In: (2011) Proceeding of ADSA-CSAS-ASAS Joint Annual Meeting. July, 10-14, New Orleans, LO.

The reduction of Salmonella prevalence in food animals in Europe is regulated by EU Reg. 2160/2003, EU Reg. 1003/2005 and others. The purpose of these regulations is to detect and control Salmonella strains that represent a threat to public health and to ensure that preventive measures at each stage of production are taken. In this…

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Dietary inclusion of a microencapsulated blend of organic acids and pure botanicals impacts intestinal health in weaned pigs

E. Grilli, B. Tugnoli, B., S. Seabold, A. J . Moeser, A. Piva, and C. H. Stahl.
In: (2012) XII Interantional Symposium of Digestive Physiology of Pigs. May 29th-June 1st, Keystone, CO, USA.

AviPlus®S (Vetagro SpA, ltaly) is a microencapsulated blend of sorbic, citric acid, thymol and vanillin. Although dietary inclusion of organic acids and botanicals has been shown to improve pig performance, the mechanism behind their efficacy has yet to be elucidated . The objective of this study was to assess the impact of dietary inclusion of…

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Effect of an in-feed microencapsulated blend of organic acids and nature-identical compounds in pigs experimentally infected with Salmonella enterica Ser-typhymurium

Alborali GL, Grilli E., Zanoni MG, Grassi A, Fantinati P, Foresti F., Piva A.
In: (2012) Proceeding of 22nd INTERNATIONAL PIG VETERINARY SOCIETY CONGRESS. June, 10-13, Jeju, Korea.

Salmonella typhymurium is the predominant serotype found in pig carcasses in Europe and several strains are resistant to antibiotics . Risk-based analyses were conducted in Danish pork Salmonella program. Biosecurity and feed play a significant role in Salmonella control in farm. Gut health is increasingly being shown to be effective against intestinalpathogens and is essential…

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Microencapsulated zinc oxide on piglets growth performance and intestinal architecture

E. Grilli, B. Tugnoli, F. Vitari, A. Piva, and A. Prandini.
In: (2013) Proceedings of ADSA-ASAS Joint Annual Meeting. July,8-12, Indianapolis, IN. J. Anim. Sci. Vol. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1

The aim was to compare low doses of microencapsulated zinc oxide (ZnO; Zincoret) in the diet of piglets with pharmacological level of ZnO on growth and ileal architecture. 144 weaned piglets, divided in 36 pens (n = 9), received a basal diet (NC; Zn at 45 mg/kg) or the basal diet with ZnO at 2850…

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Dietary inclusion of low doses of microencapsulated zinc oxide affects inflammatory cytokine and tight junction protein expression in the ileum of piglets.

E. Grilli, B. Tugnoli, F. Vitari, and A. Piva.
In: (2013) Proceedings of ADSA-ASAS Joint Annual Meeting. July,8-12, Indianapolis, IN. J. Anim. Sci. Vol. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1

Aim of this study was to investigate the expression of inflammation markers and tight junctions protein (TJ) in the ileum of piglets fed with low doses of microencapsulated zinc oxide (ZnO; Zincoret, Vetagro SpA, Italy) in comparison with either a pharmaceutical dose of free ZnO (posi- tive control) or a negative control. Twenty-four pigs weaned…

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Organic Acid Blend with Pure Botanical Product Treatment Reduces Escherichia coli and Salmonella Populations in Pure Culture and in In Vitro Mixed Ruminal Microorganism Fermentations

Ester Grilli, Riccardo Bari, Andrea Piva, Tom S. Edrington, Dipti W. Pitta, William E. Pinchak, David J. Nisbet and Todd R. Callaway
In: Foodborne Pathogens And Disease (2015) 12:56-61

Foodborne pathogenic bacteria can live in the intestinal tract of food animals and can be transmitted to humans via food or indirectly through animal or fecal contact. Organic acid blend products have been used as nonantibiotic modifiers of the gastrointestinal fermentation of food animals to improve growth performance efficiency. However, the impact of these organic…

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Microencapsulated Sorbic Acid and Pure Botanicals Affect Salmonella Typhimurium Shedding in Pigs: A Close-Up Look from Weaning to Slaughter in Controlled and Field Conditions

Ester Grilli, Fabio Foresti, Benedetta Tugnoli, Mattia Fustini, Maria G. Zanoni, Paolo Pasquali, Todd R. Callaway, Andrea Piva and Giovanni L. Alborali
In: Foodborne Pathogens and Disease, October 2015, 12(10): 813-819.

The aim of this study was to assess the efficacy of a combination of sorbic acid, thymol, and carvacrol in reducing the prevalence and shedding level of Salmonella Typhimurium in pigs either in a controlled challenge environment or in a production setting. In the first study, 24 weaned piglets were separated in 4 isolation units…

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Low doses of microencapsulated zinc oxide improve performance and modulate the ileum architecture, inflammatory cytokines and tight junctions expression of weaned pigs

E. Grilli, B. Tugnoli, F. Vitari, C. Domeneghini, M. Morlacchini, A. Piva and A. Prandini
In: Animal 9, 11 (2015); 1760-1768

The aim of this study was to compare low doses of microencapsulated v. pharmacological ZnO in the diet of piglets on growth performance, ileum health status and architecture. One hundred and forty-four piglets weaned at 28 days and divided in 36 pens (two males and two females per pen), received a basal diet (control, Zn…

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Low doses of microencapsulated zinc oxide improve performance and modulate the ileum architecture, inflammatory cytokines and tight junctions expression of weaned pigs

E. Grilli, B. Tugnoli, F. Vitari, C. Domeneghini, M. Morlacchini, A. Piva and A. Prandini
In: Animal 9, 11 (2015); 1760-1768

The aim of this study was to compare low doses of microencapsulated v. pharmacological ZnO in the diet of piglets on growth performance, ileum health status and architecture. One hundred and forty-four piglets weaned at 28 days and divided in 36 pens (two males and two females per pen), received a basal diet (control, Zn…

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