Aviplus® S

AviPlus® S is the 3rd generation of VETAGRO products for swine. A synergistic microencapsulated blend of organic acids and nature-identical compounds. AviPlus®S is registered at EU level as feed additive.

AviPlus® S is the 3rd generation of Vetagro innovative products for swine. AviPlus® S is a EU zootechnical feed additive to increase the growth rate and feed efficiency of healthy pigs.

Conditions like stress at weaning and dysbacteriosis, which all affect intestinal health, integrity and functioning of the gut, have an impact on feed efficiency. AviPlus® S may help restoring the integrity of the intestinal epithelial lining thus improving growth performance and FCR in pigs. AviPlus® S mechanism of action is based on the unique properties of its ingredients which synergistically improve the intestinal barrier function thus increasing the efficiency of nutrient absorption and growth.

AviPlus® S is fully traceable in premixes, complete feed, and even along the gastro-intestinal tract. The absolute innovation of AviPlus® S resulting from 30 years of global market experience has been proven by international patents.


REGULATORY

The EU Commission approved the use of AviPlus® S as a zootechnical feed additive with the identification number 4d3 for safe and effective swine production. AviPlus® S zootechnical performance, as reviewed and approved by EFSA under EU conditions, increases growth rate and improves feed efficiency in healthy swines. AviPlus® S is safe for the animals, the consumer and the environment as stated by the European Union.

For more information please download the full text of the EFSA scientific opinion and the Commission Implementing Regulation (EU) No 1117/2010 of 2 December 2010 from the list beneath.


Microencapsulated feed additives to reduce Salmonella shedding

E. Grilli, R. Bari, A. Piva, B. Tugnoli, and T. R. Callaway
In: (2011) Proceeding of ADSA-CSAS-ASAS Joint Annual Meeting. July, 10-14, New Orleans, LO.

The reduction of Salmonella prevalence in food animals in Europe is regulated by EU Reg. 2160/2003, EU Reg. 1003/2005 and others. The purpose of these regulations is to detect and control Salmonella strains that represent a threat to public health and to ensure that preventive measures at each stage of production are taken. In this…

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Dietary inclusion of a microencapsulated blend of organic acids and pure botanicals impacts intestinal health in weaned pigs

E. Grilli, B. Tugnoli, B., S. Seabold, A. J . Moeser, A. Piva, and C. H. Stahl.
In: (2012) XII Interantional Symposium of Digestive Physiology of Pigs. May 29th-June 1st, Keystone, CO, USA.

AviPlus®S (Vetagro SpA, ltaly) is a microencapsulated blend of sorbic, citric acid, thymol and vanillin. Although dietary inclusion of organic acids and botanicals has been shown to improve pig performance, the mechanism behind their efficacy has yet to be elucidated . The objective of this study was to assess the impact of dietary inclusion of…

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Effect of an in-feed microencapsulated blend of organic acids and nature-identical compounds in pigs experimentally infected with Salmonella enterica Ser-typhymurium

Alborali GL, Grilli E., Zanoni MG, Grassi A, Fantinati P, Foresti F., Piva A.
In: (2012) Proceeding of 22nd INTERNATIONAL PIG VETERINARY SOCIETY CONGRESS. June, 10-13, Jeju, Korea.

Salmonella typhymurium is the predominant serotype found in pig carcasses in Europe and several strains are resistant to antibiotics . Risk-based analyses were conducted in Danish pork Salmonella program. Biosecurity and feed play a significant role in Salmonella control in farm. Gut health is increasingly being shown to be effective against intestinalpathogens and is essential…

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Microencapsulated zinc oxide on piglets growth performance and intestinal architecture

E. Grilli, B. Tugnoli, F. Vitari, A. Piva, and A. Prandini.
In: (2013) Proceedings of ADSA-ASAS Joint Annual Meeting. July,8-12, Indianapolis, IN. J. Anim. Sci. Vol. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1

The aim was to compare low doses of microencapsulated zinc oxide (ZnO; Zincoret) in the diet of piglets with pharmacological level of ZnO on growth and ileal architecture. 144 weaned piglets, divided in 36 pens (n = 9), received a basal diet (NC; Zn at 45 mg/kg) or the basal diet with ZnO at 2850…

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Dietary inclusion of low doses of microencapsulated zinc oxide affects inflammatory cytokine and tight junction protein expression in the ileum of piglets.

E. Grilli, B. Tugnoli, F. Vitari, and A. Piva.
In: (2013) Proceedings of ADSA-ASAS Joint Annual Meeting. July,8-12, Indianapolis, IN. J. Anim. Sci. Vol. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1

Aim of this study was to investigate the expression of inflammation markers and tight junctions protein (TJ) in the ileum of piglets fed with low doses of microencapsulated zinc oxide (ZnO; Zincoret, Vetagro SpA, Italy) in comparison with either a pharmaceutical dose of free ZnO (posi- tive control) or a negative control. Twenty-four pigs weaned…

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Organic Acid Blend with Pure Botanical Product Treatment Reduces Escherichia coli and Salmonella Populations in Pure Culture and in In Vitro Mixed Ruminal Microorganism Fermentations

Ester Grilli, Riccardo Bari, Andrea Piva, Tom S. Edrington, Dipti W. Pitta, William E. Pinchak, David J. Nisbet and Todd R. Callaway
In: Foodborne Pathogens And Disease (2015) 12:56-61

Foodborne pathogenic bacteria can live in the intestinal tract of food animals and can be transmitted to humans via food or indirectly through animal or fecal contact. Organic acid blend products have been used as nonantibiotic modifiers of the gastrointestinal fermentation of food animals to improve growth performance efficiency. However, the impact of these organic…

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Microencapsulated Sorbic Acid and Pure Botanicals Affect Salmonella Typhimurium Shedding in Pigs: A Close-Up Look from Weaning to Slaughter in Controlled and Field Conditions

Ester Grilli, Fabio Foresti, Benedetta Tugnoli, Mattia Fustini, Maria G. Zanoni, Paolo Pasquali, Todd R. Callaway, Andrea Piva and Giovanni L. Alborali
In: Foodborne Pathogens and Disease, October 2015, 12(10): 813-819.

The aim of this study was to assess the efficacy of a combination of sorbic acid, thymol, and carvacrol in reducing the prevalence and shedding level of Salmonella Typhimurium in pigs either in a controlled challenge environment or in a production setting. In the first study, 24 weaned piglets were separated in 4 isolation units…

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Low doses of microencapsulated zinc oxide improve performance and modulate the ileum architecture, inflammatory cytokines and tight junctions expression of weaned pigs

E. Grilli, B. Tugnoli, F. Vitari, C. Domeneghini, M. Morlacchini, A. Piva and A. Prandini
In: Animal 9, 11 (2015); 1760-1768

The aim of this study was to compare low doses of microencapsulated v. pharmacological ZnO in the diet of piglets on growth performance, ileum health status and architecture. One hundred and forty-four piglets weaned at 28 days and divided in 36 pens (two males and two females per pen), received a basal diet (control, Zn…

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Low doses of microencapsulated zinc oxide improve performance and modulate the ileum architecture, inflammatory cytokines and tight junctions expression of weaned pigs

E. Grilli, B. Tugnoli, F. Vitari, C. Domeneghini, M. Morlacchini, A. Piva and A. Prandini
In: Animal 9, 11 (2015); 1760-1768

The aim of this study was to compare low doses of microencapsulated v. pharmacological ZnO in the diet of piglets on growth performance, ileum health status and architecture. One hundred and forty-four piglets weaned at 28 days and divided in 36 pens (two males and two females per pen), received a basal diet (control, Zn…

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