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• Rumen-protected methionine: a boost for primiparous dairy cows performance

  Methionine is considered the most limiting essential amino acid for ruminants (Schwab & Broderick, 2017). This element has a pivotal role in their productive performance and nitrogen efficiency.

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• Organic acid and plant botanical supplementation in heat-stressed Holstein calves

  Our findings in Holstein calves are early evidence that dietary microencapsulated OA/PB feeding is a means to partially restore feed intake and average daily gain post-weaning when challenged by heat exposure.

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• Effects of heat stress and dietary organic acids and botanicals on hepatic one-carbon metabolism

  Heat stress develops with methyl donor deficiency in parallel with an impaired N metabolism. The supplementation of OA/PB improves the remethylation capacity in the liver. On-going transcriptomic analyses will provide a better understanding of the hepatic metabolism of dairy cows exposed to heat stress.

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• Effects of ambient heat exposure and dietary organic acids and pure botanicals on gut permeability and milk production

  Heat exposure compromises the gastrointestinal barrier and leads to inflammation in non-ruminants. Our results indicate that heat stress increases gut permeability and inflammation markers rapidly and independently of dietary intake.

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• Effects of feeding 2 rumen-protected choline sources during the transition period on Holstein dairy cows performance and blood metabolites

  During the first weeks of lactation, dairy cows typically experience negative energy balance, leading to the mobilization of body reserves. This predisposes early lactating cows toward metabolic diseases, such as fatty liver syndrome and ketosis.

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• Thymol as an Adjuvant to Restore Antibiotic Efficacy and Reduce Antimicrobial Resistance and Virulence Gene Expression in Enterotoxigenic Escherichia coli Strains

  The aim of this study was to investigate the potential adjuvant effect of thymol to re-establish antibiotic efficacy against highly resistant ETEC field strains. Secondly, we evaluated the modulation of virulence and antibiotic resistance genes.

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• A mixture of organic acids and thymol protects primary chicken intestinal epithelial cells from Clostridium perfringens infection in vitro

  In this study, the protective effects of a blend of thymol and organic acids against the effects of Clostridium perfringens type A on chicken intestinal epithelial cells were investigated and compared to bacitracin, a widely used antibiotic in poultry production.

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• Dual Antimicrobial Effect of Medium-Chain Fatty Acids against an Italian Multidrug Resistant Brachyspira hyodysenteriae Strain

  In this study we tested four antibiotics (tylosin, lincomycin, doxycycline, and tiamulin) and medium-chain fatty acids (MCFA; hexanoic, octanoic, decanoic, and dodecanoic acid) against an Italian field strain of B. hyodysenteriae and the ATCC 27164 strain as reference.

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• Phenol-Rich Botanicals Modulate Oxidative Stress and Epithelial Integrity in Intestinal Epithelial Cells

  The aim of this study was to screen the activity of different sources of phenol compounds on intestinal oxidation and barrier integrity in vitro.

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• Phenol-Rich Botanicals Modulate Oxidative Stress and Epithelial Integrity in Intestinal Epithelial Cells

  The aim of this study was to screen the activity of different sources of phenol compounds on intestinal oxidation and barrier integrity in vitro.

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• Phenol-Rich Botanicals Modulate Oxidative Stress and Epithelial Integrity in Intestinal Epithelial Cells

  The aim of this study was to screen the activity of different sources of phenol compounds on intestinal oxidation and barrier integrity in vitro.

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• Phenol-Rich Botanicals Modulate Oxidative Stress and Epithelial Integrity in Intestinal Epithelial Cells

  The aim of this study was to screen the activity of different sources of phenol compounds on intestinal oxidation and barrier integrity in vitro.

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• Intestinal health helps preventing milk loss linked to ketosis and heat stress

  From an economic point of view, the lack of metabolic adaptation at the beginning of lactation (ketosis) and heat stress are two of the most important diseases for dairy cows as they seriously jeopardize the competitiveness of world animal husbandry and significantly reduce its efficiency.

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• Effects of feeding 2 rumen-protected choline sources during the transition period on Holstein dairy cows performance and blood metabolites

  During the first weeks of lactation, dairy cows typically experience negative energy balance, leading to the mobilization of body reserves. This predisposes early lactating cows toward metabolic diseases, such as fatty liver syndrome and ketosis.

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• Assessing intestinal health. In vitro and ex vivo gut barrier models of farm animals: benefits and limitations

  The concept of “gut health" is not well defined, but this concept has begun to play a very important role in the field of animal science. However, a clear definition of GIT health and the means by which to measure it are lacking. In vitro and ex vivo models can facilitate these studies, creating well-controlled and repeatable conditions to understand how to improve animal gut health.

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