Swine Press
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The aim of this study was to investigate the potential adjuvant effect of thymol to re-establish antibiotic efficacy against highly resistant ETEC field strains. Secondly, we evaluated the modulation of virulence and antibiotic resistance genes.
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In this study we tested four antibiotics (tylosin, lincomycin, doxycycline, and tiamulin) and medium-chain fatty acids (MCFA; hexanoic, octanoic, decanoic, and dodecanoic acid) against an Italian field strain of B. hyodysenteriae and the ATCC 27164 strain as reference.
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The aim of this study was to screen the activity of different sources of phenol compounds on intestinal oxidation and barrier integrity in vitro.
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The concept of “gut health" is not well defined, but this concept has begun to play a very important role in the field of animal science. However, a clear definition of GIT health and the means by which to measure it are lacking. In vitro and ex vivo models can facilitate these studies, creating well-controlled and repeatable conditions to understand how to improve animal gut health.
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Post-weaning diarrhoea is а striking issue of the pig industry and its onset is primarily associated with Escherichia coli К88 (Е. coli). То assess the effectiveness of bioactives in preventing the damages exerted bу the pathogen, the aim of this study was to set-up an in vitro model to mimic an Е. coli challenge on intestinal cells.
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Organic acids have been used for a long time to support pig growth particularly at weaning, and more recently have become the number one alternative to growth promoters to improve the production efficiency of pigs.
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Providing microencapsulated organic acids and botanicals during the nursery phase increased G:F in the early and overall nursery phase, but there was no effect on overall wean-to-finish performance.
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The use of NIC allows us to properly combine pure compounds, according to the target to achieve. Thus, they represent a promising non-antibiotic tool to allow better intestinal health and general health status, thereby leading to improved growth performance.
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A real-time PCR study highlighted a significant downregulation of the main virulence genes of Salmonella (hilA, prgH, invA, sipA, sipC, sipD, sopB, sopE2). These findings indicate that thymol and carvacrol could be good candidates for the control of Salmonella typhimurium in pigs.
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The purposes of this study were to investigate the presence of markers of the endocannabinoid system and the chemosensing system in the pig gut and, second, to determine if thymol modulates these markers.
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The endocannabinoid system (ECS) has opened the door to novel therapeutical approaches targeting cancer, pain, anxiety, stress, and inflammatory diseases. The ECS is ubiquitously expressed in almost all members of Animalia, but its precise localization outside the central nervous system is still under investigation.
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Butyric acid is widely used in pig production as feed additive to improve growth performance at weaning, based on its intestinal health-promoting action. The aim of this study was to evaluate the intestinal architecture and expression of inflammatory cytokines and tight junctions (TJ) markers in weaning piglets fed with tributyrin, either free or microencapsulated, as dietary source of butyric acid.
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Aim of this study was to investigate the expression of inflammation markers and tight junctions protein (TJ) in the ileum of piglets fed with low doses of microencapsulated zinc oxide (ZnO; Zincoret, Vetagro SpA, Italy) in comparison with either a pharmaceutical dose of free ZnO (positive control) or a negative control.
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Two studies were conducted to assess the effects of dietary protein and Lys reduction on growth performance, carcass quality, N excretion, and plasma N profile in growing-finishing pigs from 35 to 180 kg.
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The aim of this study was to compare low doses of microencapsulated v. pharmacological ZnO in the diet of piglets on growth performance, ileum health status and architecture.
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The objective of this study was to evaluate the effects of different organic acids on bacterial growth and ammonia production by swine cecal microflora in an in vitro fermentation system.
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The increased use of slow-release organic acids in swine nutrition has prompted more research to assess their possible role in modulating the intestinal microflora as an alternative to antibiotics.
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Zinc is one of the most important trace elements in animal nutrition because it ensures the activity of several enzymes involved in cellular signalling, digestion, cellular respiration, and nucleic acid metabolism...
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Organic acids, such as citric and sorbic acid, and pure plant-derived constituents, like monoterpens and aldehydes, have a long history of use in pig feeding as alternatives to antibiotic growth promoters. However, their effects on the intestinal barrier function and inflammation have never been investigated.
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Weaning is a physiological and unavoidable period in mammals life but, at the same time, it is extremely stressful. There are several stressors in animal life at this age, both psychosocial and physical: separation from the sow and the littermate, dietary and environmental change, a new social hierarchy with unknown piglets.
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This study was conducted to evaluate the effect of microencapsulated organic acids and essential oils (MOE) on reproductive performance, nutrient digestibility, piglet diarrhoea score, and blood profiles in sows and suckling piglets.
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Background: positive effects of organic acids and essential oils (MOE) on livestock are well documented. Microencapsulation allows the slow release of core materials in a specific moment or environment.
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Intestinal health is a concern for everybody working in pig production. Enteric diseases are an often seen problem in raising piglets that can cause severe economic losses and reduced piglet performance.
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The aim of the study was to investigate the effects of supplementation of a microencapsulated blend of tributyrin and lactitol (TL) to a standard European (EU) diet without antibiotic growth promoters on intestinal metabolism and mucosa development of weaned piglets and to compare it with a standard US diet containing animal proteins, zinc oxide, copper sulfate, and carbadox.
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At 28 d after birth, the piglets were weighed and allotted into four groups and fed a standard nonmedicated diet (control) or the control diet with tributyrin (butanoic acid 1,2,3-propanetriyl ester; 10 g/kg), or with lactitol (β-Dgalactopyranosyl-(1→4)-D-sorbitol; 3 g/kg), or with tributyrin (10 g/kg) plus lactitol (3 g/kg).
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The aim of this study was to assess the efficacy of a combination of sorbic acid, thymol, and carvacrol in reducing the prevalence and shedding level of Salmonella Typhimurium in pigs either in a controlled challenge environment or in a production setting.
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The purpose of the present work was to investigate the in vivo concentrations of sorbic acid and vanillin as markers of the fate of organic acids (OA) and natural identical flavors (NIF) from a microencapsulated mixture and from the same mixture non-microencapsulated, and the possible consequences on the intestinal microbial fermentation.
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A total of 90 pigs (6.47 ± 0.27 kg; 21 d of age) were used in this 22 wk feeding trial to evaluate the effect of microencapsulated complex of organic acids and essential oils (MOE) on growth performance, nutrient retention, blood profile, fecal microflora, and lean meat percentage in pigs.
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One-hundred and seventy weaning pigs were divided in two groups, and housed in 34 pens (17 replicates, 5 pigs each). Piglets received a basal diet without (control diet, CTR) or with the addition of a microencapsulated blend of organic acids and nature identical compounds at 3 kg/ton (AviPlus®, EP1391155B1, Vetagro SpA, Italy).
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A total of 125 crossbred pigs with initial body weight (BW) of 7.66 ± 1.30 kg were randomly distributed into one of five dietary treatments. Each treatment had five replicate pens with five pigs per pen.
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Despite common use, stress is medically defined as the functional response of an organism to any kind of stimulus (stressor, that can be of any intensity and duration). Stressors can have different nature and alter the physiological equilibrium of the organism.
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Post-weaning diarrhoea (PWD) is one of the long-standing challenges in pig husbandry. Due to the risks of resistance caused by antibiotics (AB) misuse, conventional treatments against Escherichia coli K88 (E. coli K88), the PWD etiological agent, urgently need to be replaced. Organic acids (OA) and nature-identical compounds (NIC) are currently finding a central role in infection management thanks to their recognized antimicrobial activity.
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This article reviews the utilization of ZnO in piglets, the biological rationale behind its powerful activity, and the emerging threats that are leading towards a significant reduction in its use. Finally, a wide analysis of the strengths and weaknesses of innovative alternative strategies to manage PWD at the nutritional level is given.